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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Gilbert's syndrome ： ウィキペディア英語版 Gilbert's syndrome Gilbert's syndrome ( ),〔 often shortened to GS, also called Gilbert–Meulengracht syndrome, is a common genetic liver disorder found in 3-12% of the population.〔http://www.mayoclinic.org/diseases-conditions/gilberts-syndrome/basics/definition/con-20024904〕〔http://www.liverfoundation.org/abouttheliver/info/gilbertsyndrome/〕〔http://www.nhs.uk/conditions/gilbertssyndrome/Pages/Introduction.aspx〕〔http://ghr.nlm.nih.gov/condition/gilbert-syndrome〕〔 It produces elevated levels of unconjugated bilirubin in the bloodstream (hyperbilirubinemia), but this normally has no serious consequences, although mild jaundice may appear under conditions of exertion or stress. The cause of this hyperbilirubinemia is the reduced activity of the enzyme glucuronyltransferase, which conjugates bilirubin and a few other lipophilic molecules. Conjugation renders the bilirubin water-soluble, after which it is excreted in bile into the duodenum. There are a number of variants of the gene for the enzyme, so the genetic basis of the condition is complex. ==Signs and symptoms== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Gilbert's syndrome」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.